DNA Binding Motif

Accessions: GCM2_DLX3_2 (HumanTF2 1.0)
Names: GCM2_DLX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: aTrcGGGywrkdtAAttr
Weblogo:
PSSM: P0 A C G T
01 5865 1430 2327 597 a
02 813 940 514 8192 T
03 3281 624 4911 11 r
04 3568 8192 3419 2529 c
05 1721 173 8192 1561 G
06 4 19 8192 54 G
07 11 2 8192 31 G
08 1241 2574 879 3499 y
09 2368 1501 1866 2457 w
10 2399 1501 2269 2023 r
11 2006 1642 2472 2072 k
12 2340 1457 2185 2210 d
13 2055 1485 502 8192 t
14 8192 781 1863 943 A
15 8192 138 469 316 A
16 1136 1048 1777 8192 t
17 2021 1804 2704 5488 t
18 3564 1193 4629 1978 r
Type: Heterodimer
Binding TFs: DLX3_TF2 (Homeobox domain)
GCM2_TF1 (GCM motif protein)
DLX3_Crystal (Homeobox domain)
DLX3_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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