DNA Binding Motif

						

			
Accessions: ETV2_CLOCK (HumanTF2 1.0)

			
Names: ETV2_CLOCK
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: rmCACGTGbcayacCGGAwry
Weblogo: 
PSSM: P0      A      C      G      T
01   3910   2284   5424   2012      r
02   5907   4216   2591    916      m
03   1088  13630     30     82      C
04  13630     72   1322     70      A
05      5  13630     83   1095      C
06   1819      0  13630     37      G
07     99   1169     62  13630      T
08      8      1  13630   1356      G
09    705   4007   4307   4610      b
10   2377   4990   2882   3380      c
11   4277   3310   2668   3375      a
12   1511   4637   3260   4223      y
13   5634   2301   2771   2924      a
14   4469  13630   2682   1287      c
15   3678  13630    718      6      C
16      2      5  13630      4      G
17     10      6  13630     10      G
18  13630      3      7     12      A
19   5681   1159    123   7949      w
20   4795   2296   8835    990      r
21   1063   7648   3636   5981      y
Type: Heterodimer
Binding TFs: CLOCK_TF1 / CLOCK_TF2 (Helix-loop-helix DNA-binding domain)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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