DNA Binding Motif

						

			
Accessions: ERF_DLX2_2 (HumanTF2 1.0)

			
Names: ERF_DLX2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: rsmGGAwrtsrvymaTTa
Weblogo: 
PSSM: P0      A      C      G      T
01    474    147    257    148      r
02    169    421    309    105      s
03    418    730     24      0      m
04      2      0    730      8      G
05      2      2    730     19      G
06    730     17     11      0      A
07    730     95      0    357      w
08    294     73    311     53      r
09    116    147     81    387      t
10    166    186    263    116      s
11    210    150    315     55      r
12    200    240    216     75      v
13    110    357     67    374      y
14    477    253     94     41      m
15    730    253    122    110      a
16     25     32     50    730      T
17     50    118     11    730      T
18    730     91     97    176      a
Type: Heterodimer
Binding TFs: DLX2_TF2 (Homeobox domain, Homeobox protein distal-less-like N terminal )
DLX2_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
ERF_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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