DNA Binding Motif

Accessions: UP00419A_1 (UniPROBE 20160601)
Names: AU019198, C76795, Prf, Pu.1-related factor, Spi-C transcription factor (Spi-1/PU.1 related), Spic, Transcription factor Spi-C
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 14
Consensus: rAAaGmGGAAGTwd
Weblogo:
PSSM: P0 A C G T
01 0.37 0.18 0.30 0.15 r
02 0.73 0.06 0.04 0.16 A
03 0.71 0.05 0.11 0.14 A
04 0.64 0.06 0.07 0.23 a
05 0.13 0.11 0.69 0.08 G
06 0.27 0.52 0.21 0.01 m
07 0.02 0 0.98 0 G
08 0 0 0.99 0 G
09 0.98 0 0 0.01 A
10 0.97 0 0 0.02 A
11 0.04 0.13 0.82 0.01 G
12 0.03 0.05 0.02 0.91 T
13 0.32 0.05 0.17 0.46 w
14 0.34 0.11 0.28 0.26 d
Binding TFs: UP00419A (Ets-domain)
Binding Sites: AACTTCCC
AACTTCCG
AACTTCCT
AAGAGGAA
ACTTCCCC
ACTTCCCT
ACTTCCGC
ACTTCCGG
ACTTCCTA
ACTTCCTC
ACTTCCTG
AGCGGAAG
AGGAAGTA
AGGAAGTG
CACTTCCG
CGGAAGTA
CTTCCGCA
GGAAGTAA
GGGAAGTA
TTCCGGAA
Publications: Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed]

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