DNA Binding Motif

						

			
Accessions: 2pi0_B (3D-footprint 20231221)

			
Names: Interferon regulatory factor 3
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-B enhancer
Length: 4
Consensus: tTtC
Weblogo: 
PSSM: P0      A      C      G      T
01     12     12     12     60      t
02      0      0      0     96      T
03     12     12     12     60      t
04      0     84      0     12      C
Binding TFs: 2pi0_B (Interferon regulatory factor transcription factor)
Binding Sites: 2pi0_E
2pi0_F
			
Publications: Escalante C.R, Nistal-Villán E, Shen L, García-Sastre A, Aggarwal A.K. Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-beta enhancer. Molecular cell 26:703-16 (2007). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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