DNA Binding Motif

						

			
Accessions: THRB_methyl_2 (HT-SELEX2 May2017)

			
Names: THRB
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Length: 16
Consensus: arrGGTCrTGACCyyk
Weblogo: 
PSSM: P0      A      C      G      T
01    722    489    556    489      a
02   1047    424   1210    335      r
03   1235     18   1022     13      r
04     32      9   2257    115      G
05     27      6   2257    441      G
06      9     77    337   2257      T
07     31   2257     81    235      C
08    757     12   1500     13      r
09     10    623     16   2257      T
10    343     81   2257     33      G
11   2257    215     61     14      A
12    650   2257     13     19      C
13    106   2257      9     34      C
14     11    933     35   1324      y
15    428   1103    634   1154      y
16    508    496    582    671      k
Binding TFs: THRB (Zinc finger, C4 type (two domains))
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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