DNA Binding Motif

						

			
Accessions: TLX3_4 (HT-SELEX2 May2017), UN0138.1 (JASPAR 2024)

			
Names: TLX3
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1, JASPAR 2024 2
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 22
Consensus: kAATTGbkbkdhhsmvCAATTm
Weblogo: 
PSSM: P0      A      C      G      T
01     38     38     74     62      k
02    213      5      7      5      A
03    213      0      0      3      A
04     16      5      2    213      T
05     22     12     26    213      T
06      5      4    213      2      G
07     32     68     56     57      b
08     36     51     60     66      k
09     35     65     59     54      b
10     51     41     54     66      k
11     66     25     61     61      d
12     64     58     34     58      h
13     63     59     36     55      h
14     51     60     64     37      s
15     71     55     51     36      m
16     56     58     71     27      v
17      1    213      4      4      C
18    213     28     17     15      A
19    213      1      5     13      A
20      4      7      1    213      T
21      6      7      5    213      T
22     62     75     34     42      m
Type: Heterodimer
Binding TFs: TLX3 (Homeobox domain)
O43711 (Homeobox domain)
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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