DNA Binding Motif

						

			
Accessions: ETV2_RFX5_1 (HumanTF2 1.0)

			
Names: ETV2_RFX5
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: crCwTCCGsysshrGCAACss
Weblogo: 
PSSM: P0      A      C      G      T
01    423    842    330    325      c
02   1652    358    786    119      r
03      7   1837     83    495      C
04    781      6     71   1764      w
05     11      0      5   1920      T
06      6   1921      8      2      C
07      0   1921      2      2      C
08     22     24   1875    222      G
09    312    970   1351    386      s
10    298   1044    262    778      y
11    321    616    792    191      s
12    418    576    567    359      s
13    541    512    349    519      h
14    536    469    652    264      r
15    442    159   1849    137      G
16    155   1854     78    523      C
17   1887    124    129    144      A
18   1912    164     71    108      A
19     84   1908     86     64      C
20    499    982    829    250      s
21    468    678    560    215      s
Type: Heterodimer
Binding TFs: RFX5_TF2 (RFX DNA-binding domain, Poxvirus D5 protein-like)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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