DNA Binding Motif

Accessions: TEAD4_FOXI1_2_3 (HumanTF2 1.0)
Names: TEAD4_FOXI1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 27
Consensus: GCATwCCryrmmmwsyymmyrTmAACA
Weblogo:
PSSM: P0 A C G T
01 59 0 190 21 G
02 3 249 6 0 C
03 249 11 4 0 A
04 0 17 3 249 T
05 74 4 15 175 w
06 0 249 36 0 C
07 13 249 0 32 C
08 118 27 67 37 r
09 59 72 54 64 y
10 70 54 93 32 r
11 81 91 55 23 m
12 63 99 41 47 m
13 71 92 42 44 m
14 66 56 34 92 w
15 59 69 82 40 s
16 18 106 42 83 y
17 62 84 33 70 y
18 107 63 46 34 m
19 92 88 32 37 m
20 35 126 15 73 y
21 93 12 156 0 r
22 25 52 13 249 T
23 169 80 13 0 m
24 249 74 6 9 A
25 249 27 31 37 A
26 0 249 0 43 C
27 249 9 23 1 A
Type: Heterodimer
Binding TFs: FOXI1_TF2 (Fork head domain)
TEAD4_TF1 (TEA/ATTS domain family)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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