DNA Binding Motif

						

			
Accessions: HOXB13_ONECUT2_2 (HumanTF2 1.0)

			
Names: HOXB13_ONECUT2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: HT-SELEX; PWM is from validation experiment performed with full-length TFs and is not included into the dendrograms
Length: 16
Consensus: CYcrTAAAwaTCGaty
Weblogo: 
PSSM: P0      A      C      G      T
01     52    365     69     20      C
02      0    154      5    349      Y
03    108    317      8     73      c
04    204      2    302      7      r
05      1     28     17    506      T
06    506      1     10     42      A
07    506      3      0      0      A
08    506     17     10     67      A
09    196     54      1    310      w
10    506    163     49     80      a
11     69    143      6    506      T
12      0    410     28     96      C
13     63     71    506     19      G
14    506    107     83     88      a
15     45    100     57    406      t
16     65    276     79    230      y
Type: Heterodimer
Binding TFs: HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
ONECUT2_TF2 (Homeobox domain, CUT domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
ONECUT2_Full (Homeobox domain, CUT domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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