DNA Binding Motif

						

			
Accessions: 3m9e_AB (3D-footprint 20231221)

			
Names: Thyroid hormone receptor beta
Organisms: Rattus norvegicus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Thyroid hormone beta DNA binding domain homodimer with inverted palindrome TRE
Length: 18
Consensus: TGACCtnnnnnnrGGTCA
Weblogo: 
PSSM: P0      A      C      G      T
01      8      9      9     70      T
02      0      0     96      0      G
03     73     11      6      6      A
04      0     96      0      0      C
05      0     96      0      0      C
06      9     21      6     60      t
07     24     24     24     24      n
08     24     24     24     24      n
09     24     24     24     24      n
10     24     24     24     24      n
11     24     24     24     24      n
12     24     24     24     24      n
13     59      3     28      6      r
14      0      0     96      0      G
15      0      0     96      0      G
16      6      6      4     80      T
17      0     96      0      0      C
18     86      3      3      4      A
Type: Heterodimer
Binding TFs: 3m9e_A (Zinc finger, C4 type (two domains))
3m9e_B (Zinc finger, C4 type (two domains))
Binding Sites: 3m9e_C / 3m9e_D
			
Publications: Chen Y, Young M.A. Structure of a thyroid hormone receptor DNA-binding domain homodimer bound to an inverted palindrome DNA response element. Molecular endocrinology (Baltimore, Md.) 24:1650-64 (2010). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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