DNA Binding Motif

						

			
Accessions: FOSB_2 (HT-SELEX2 May2017), UN0122.1 (JASPAR 2024)

			
Names: FOSB
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1, JASPAR 2024 2
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 12
Consensus: grTGACGTCAyc
Weblogo: 
PSSM: P0      A      C      G      T
01    563    587   1658    540      g
02   2305    139   1043     30      r
03     12     56     33   3348      T
04     53     83   3348    259      G
05   3348     31     42     12      A
06     17   3348      0    143      C
07    163      2   3348      0      G
08     38     34     30   3348      T
09    252   3348     98     47      C
10   3348     30     53     13      A
11     31   1065    116   2283      y
12    585   1630    599    534      c
Type: Heterodimer
Binding TFs: P53539 (bZIP transcription factor, Basic region leucine zipper)
FOSB (bZIP transcription factor, Basic region leucine zipper)
P53539
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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