DNA Binding Motif

						

			
Accessions: PAX9_DBD (HumanTF 1.0), MA0781.1 (JASPAR 2024)

			
Names: PAX9
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 4, HT-SELEX
Length: 17
Consensus: sGTCACGCwTSAsTGmm
Weblogo: 
PSSM: P0      A      C      G      T
01    154   2410   1176    244      s
02      0      0   3811     10      G
03     67     13      6   3107      T
04      0   3775      0    171      C
05   3241     71      2      1      A
06      0   3860      0    267      C
07      0      0   3945      0      G
08      0   3695    727      0      C
09   1840     83     13   1141      w
10      1     68      0   3188      T
11      3   1412   3552      3      S
12   3083      0    468      0      A
13    622   1423    962    444      s
14      6    207      0   3132      T
15    142      8   3608    251      G
16   1249   2390    471      0      m
17   2184   1334    644    852      m
Type: Heterodimer
Binding TFs: PAX9_DBD ('Paired box' domain, Homeodomain-like domain)
P55771 ('Paired box' domain, Homeodomain-like domain)
P55771
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Wolf LV, Yang Y, Wang J, Xie Q, Braunger B, Tamm ER, Zavadil J, Cvekl A. Identification of pax6-dependent gene regulatory networks in the mouse lens. PLoS One : (2009;4(1):e4159.). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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