DNA Binding Motif

Accessions: GCM1_ETV7_1 (HumanTF2 1.0)
Names: GCM1_ETV7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: atrmGGGCGGAArydyTTCCbby
Weblogo:
PSSM: P0 A C G T
01 1620 407 472 162 a
02 631 487 515 2336 t
03 918 240 1046 39 r
04 901 1031 435 352 m
05 156 138 1432 154 G
06 148 253 1696 216 G
07 71 75 1742 187 G
08 367 3056 155 123 C
09 0 1 1736 0 G
10 5 15 1745 18 G
11 3159 19 0 107 A
12 3135 347 5 254 A
13 694 303 1512 101 r
14 322 911 203 1325 y
15 894 318 665 662 d
16 158 1093 347 1049 y
17 432 7 421 2090 T
18 263 0 12 2655 T
19 9 3298 67 52 C
20 39 3131 2 265 C
21 111 674 857 694 b
22 153 562 904 549 b
23 386 695 313 1197 y
Type: Heterodimer
Binding TFs: GCM1_TF1 (GCM motif protein)
ETV7_TF1 / ETV7_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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