DNA Binding Motif

						

			
Accessions: ARNTL_BHLHA15 (HumanTF2 1.0)

			
Names: ARNTL_BHLHA15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: rtCACGTGMacmCATATGgk
Weblogo: 
PSSM: P0      A      C      G      T
01   3140   1207   4530   1263      r
02   1140   1498   2277   5973      t
03    230   8720      0      0      C
04   8704     35      4    494      A
05      1   8569    254     38      C
06    291    117   8709      9      G
07      0     72     35   8705      T
08    304      5   8716     12      G
09   2336   5989    130    263      M
10   4381    742   1606   1989      a
11    564   4858   1795   1502      c
12   2720   5270   1244     99      m
13    159   8708     84     50      C
14   8291    163   1055    294      A
15     99   1110   1191   8582      T
16   8549    870    910     54      A
17     69    503     13   8713      T
18     49     85   8601    298      G
19    464   2065   4762   2422      g
20   1952    731   2831   3204      k
Type: Heterodimer
Binding TFs: BHLHA15_TF2 (Helix-loop-helix DNA-binding domain)
ARNTL_TF1 (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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