DNA Binding Motif

						

			
Accessions: GCM2_DRGX_2 (HumanTF2 1.0)

			
Names: GCM2_DRGX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 15
Consensus: ATrcGGGytaaTtak
Weblogo: 
PSSM: P0      A      C      G      T
01   1284    159    326     50      A
02    184     78    185   1610      T
03    458    134   1152     29      r
04    219   1185    425    179      c
05     58     56   1610      0      G
06      0     11   1610      6      G
07      0      0   1610      0      G
08    175    774    217    445      y
09    264    345    373    629      t
10   1610    562    492    204      a
11   1610    169    336    612      a
12     63    187    100   1610      T
13    277    297    192   1610      t
14   1610     97    272    632      a
15    356     78    700    476      k
Type: Heterodimer
Binding TFs: DRGX_TF2 (Homeobox domain)
GCM2_TF1 (GCM motif protein)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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