DNA Binding Motif

Accessions: 4yj0_C (3D-footprint 20231221)
Names: Doublesex- and mab-3-related transcription factor 1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the DM domain of human DMRT1 bound to 25mer target DNA
Length: 5
Consensus: TGTTG
Weblogo:
PSSM: P0 A C G T
01 9 11 9 67 T
02 0 0 96 0 G
03 9 0 11 76 T
04 0 9 1 86 T
05 9 9 67 11 G
Binding TFs: 4yj0_C (DM DNA binding domain)
Binding Sites: 4yj0_D
4yj0_E
Publications: Murphy MW, Lee JK, Rojo S, Gearhart MD, Kurahashi K, Banerjee S, Loeuille GA, Bashamboo A, McElreavey K, Zarkower D, Aihara H, Bardwell VJ. An ancient protein-DNA interaction underlying metazoan sex determination. Nat Struct Mol Biol 22:442-51 (2015). [Pubmed]

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