DNA Binding Motif

Accessions: 1zrc_B (3D-footprint 20231221)
Names: Catabolite gene activator
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: 4 Crystal structures of CAP-DNA with all base-pair substitutions at position 6, CAP-ICAP38 DNA
Length: 5
Consensus: TGTGA
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 11 9 67 9 G
03 9 11 9 67 T
04 9 9 69 9 G
05 96 0 0 0 A
Binding TFs: 1zrc_B (Cyclic nucleotide-binding domain, Bacterial regulatory proteins, crp family, Crp-like helix-turn-helix domain)
Binding Sites: 1zrc_Y
1zrc_Z
Publications: Napoli A.A, Lawson C.L, Ebright R.H, Berman H.M. Indirect readout of DNA sequence at the primary-kink site in the CAP-DNA complex: recognition of pyrimidine-purine and purine-purine steps. Journal of molecular biology 357:173-83 (2006). [Pubmed]

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