DNA Binding Motif

						

			
Accessions: GCM2_E2F8 (HumanTF2 1.0)

			
Names: GCM2_E2F8
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: ATrsGGGtwatsGcGGGAaw
Weblogo: 
PSSM: P0      A      C      G      T
01    444     37     62     40      A
02     39     59     70    551      T
03    270     63    306      0      r
04    122    356    265    123      s
05     85      0    569     43      G
06      0      0    583     27      G
07      0      0    563     45      G
08    130     79     41    332      t
09    259     32    105    186      w
10    333     26    121    103      a
11    189    116    197    487      t
12     41    272    535    111      s
13     38     41    572     14      G
14     72    570    156    112      c
15     48     17    583     63      G
16     10      0    577     47      G
17     64     59    578     97      G
18    566    121     30     68      A
19    339     32    164    123      a
20    326     45     65    146      w
Type: Heterodimer
Binding TFs: E2F8_TF2 (E2F/DP family winged-helix DNA-binding domain)
GCM2_TF1 (GCM motif protein)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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