DNA Binding Motif

						

			
Accessions: FLI1_CEBPB (HumanTF2 1.0), UN0526.1 (JASPAR 2024)

			
Names: FLI1_CEBPB, FLI1::CEBPB
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 17
Consensus: rvCGGAwrTTGCGCAAy
Weblogo: 
PSSM: P0      A      C      G      T
01   2099    234   1660    551      r
02   1031   1646   1014     68      v
03    769   3759    152     21      C
04     14      0   3759     50      G
05      8     52   3759     23      G
06   3759      4     82     24      A
07   2074    197      0   1490      w
08   1582     19   2161      0      r
09      0      4     17   3759      T
10      0      1     15   3759      T
11   1034      3   3759     64      G
12      3   3759    128     36      C
13     80      9   3759      7      G
14    150   3759     11    965      C
15   3759      4      3      0      A
16   3759      3      0      0      A
17     21   1497    430   1810      y
Type: Heterodimer
Binding TFs: Q01543 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
CEBPB_TF2 (bZIP transcription factor, Basic region leucine zipper)
FLI1_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
FLI1_Full (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
Q01543
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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