DNA Binding Motif
| Accessions: | LHX2_DBD_1 (HumanTF 1.0), MA0700.1 (JASPAR 2024) |
| Names: | LHX2 |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1, JASPAR 2024 2 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | Site type: monomeric; SELEX cycle: 4, HT-SELEX |
| Length: | 10 |
| Consensus: | rCTAATTArc |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 16039 10579 15546 6251 r 02 3769 48415 6413 8481 C 03 633 15833 67 48415 T 04 48415 6090 288 621 A 05 48415 0 63 0 A 06 0 0 0 48415 T 07 259 1120 2834 48415 T 08 48415 23 8137 520 A 09 19244 6815 15319 7038 r 10 7653 16953 11964 11845 c |
| Type: | Heterodimer |
| Binding TFs: | LHX2_DBD (Homeobox domain, Homeobox KN domain) P50458 (Homeobox domain, LIM domain, Homeobox KN domain) P50458 |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] Noyes M.B, Christensen R.G, Wakabayashi A, Stormo G.D, Brodsky M.H, Wolfe S.A. Analysis of homeodomain specificities allows the family-wide prediction of preferred recognition sites. Cell 133:1277-89 (2008). [Pubmed] |
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