DNA Binding Motif

Accessions: ETV2_SOX15_1 (HumanTF2 1.0)
Names: ETV2_SOX15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: rcCGGAWgtrvgkbywTTGT
Weblogo:
PSSM: P0 A C G T
01 441 85 342 127 r
02 122 551 231 60 c
03 44 782 28 31 C
04 6 5 782 0 G
05 0 9 782 2 G
06 782 0 11 4 A
07 782 21 0 289 W
08 192 51 525 14 g
09 68 181 36 497 t
10 225 84 344 128 r
11 257 213 211 101 v
12 186 159 284 153 g
13 79 144 253 306 k
14 8 349 224 200 b
15 106 401 75 381 y
16 518 24 63 265 w
17 116 71 93 782 T
18 41 43 52 782 T
19 152 89 782 77 G
20 83 41 38 782 T
Type: Heterodimer
Binding TFs: SOX15_TF2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
ETV2_TF1 (Ets-domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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