DNA Binding Motif

						

			
Accessions: 4xrm_B (3D-footprint 20231221)

			
Names: Homeobox protein Meis2
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: homodimer of TALE type homeobox transcription factor MEIS1 complexes with specific DNA
Length: 6
Consensus: TTGTCA
Weblogo: 
PSSM: P0      A      C      G      T
01      9      9      9     69      T
02      9     11      9     67      T
03      0      0     96      0      G
04      0      0      0     96      T
05      0     96      0      0      C
06     69      9      9      9      A
Binding TFs: 4xrm_B (Homeobox domain, Homeobox KN domain)
Binding Sites: 4xrm_L
4xrm_M
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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