DNA Binding Motif

						

			
Accessions: ERF_HES7_2_3 (HumanTF2 1.0)

			
Names: ERF_HES7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: gvCACGTGgyrkmsCGGAAry
Weblogo: 
PSSM: P0      A      C      G      T
01     21     14     68     26      g
02     50     34     35     10      v
03      2    130     15      5      C
04    130      3     28     24      A
05     18    130      9      5      C
06      0      2    130      0      G
07     11     46      2    130      T
08      3      3    130      0      G
09      9     32     57     32      g
10     11     42     14     63      y
11     39     26     44     19      r
12     23     20     50     36      k
13     62     38     15     14      m
14     17    130     75      0      s
15     17    130      0      0      C
16      0      0    130      9      G
17      0      0    130      0      G
18    130      2      5      0      A
19    130     24      2     30      A
20     48      7     66      8      r
21     11     48     14     55      y
Type: Heterodimer
Binding TFs: HES7_TF2 (Helix-loop-helix DNA-binding domain)
ERF_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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