DNA Binding Motif

						

			
Accessions: 1au7_AB (3D-footprint 20231221)

			
Names: PROTEIN PIT-1
Organisms: Rattus norvegicus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: PIT-1 MUTANT/DNA COMPLEX
Length: 14
Consensus: tcATGTATATACAT
Weblogo: 
PSSM: P0      A      C      G      T
01     10     23     10     53      t
02     10     53     12     21      c
03     96      0      0      0      A
04      0      0      0     96      T
05      0      0     96      0      G
06      0      0      0     96      T
07     96      0      0      0      A
08      0      0      0     96      T
09     96      0      0      0      A
10      0      0      0     96      T
11     96      0      0      0      A
12      0     96      0      0      C
13     85      0      0     11      A
14      0      0      0     96      T
Type: Heterodimer
Binding TFs: 1au7_A (Homeobox domain, Pou domain - N-terminal to homeobox domain)
1au7_B (Homeobox domain, Pou domain - N-terminal to homeobox domain)
Binding Sites: 1au7_C
1au7_D
			
Publications: Jacobson E.M, Li P, Leon-del-Rio A, Rosenfeld M.G, Aggarwal A.K. Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility. Genes & development 11:198-212 (1997). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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