DNA Binding Motif

Accessions: ETV2_DRGX_2 (HumanTF2 1.0)
Names: ETV2_DRGX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 13
Consensus: rcCGGAwryatTa
Weblogo:
PSSM: P0 A C G T
01 667 94 393 176 r
02 185 823 238 83 c
03 131 1060 17 0 C
04 5 0 1060 3 G
05 0 0 1060 2 G
06 1060 0 0 0 A
07 634 101 2 426 w
08 400 116 660 25 r
09 242 414 49 646 y
10 1060 83 380 64 a
11 322 130 178 1060 t
12 137 166 107 1060 T
13 1060 98 137 283 a
Type: Heterodimer
Binding TFs: DRGX_TF2 (Homeobox domain)
ETV2_TF1 (Ets-domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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