DNA Binding Motif

Accessions: TEAD4_DLX3_2 (HumanTF2 1.0)
Names: TEAD4_DLX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: rCATwCytyssTAATtr
Weblogo:
PSSM: P0 A C G T
01 1633 149 1999 178 r
02 722 3632 299 9 C
03 3632 17 431 3 A
04 63 14 12 3632 T
05 2764 84 1208 3632 w
06 87 3632 626 243 C
07 120 2468 68 976 y
08 879 669 823 1261 t
09 854 1012 847 919 y
10 885 972 1073 702 s
11 879 964 1085 704 s
12 580 510 57 3632 T
13 3632 92 852 104 A
14 3632 32 17 7 A
15 323 454 583 3632 T
16 751 920 1277 2354 t
17 1721 397 1911 714 r
Type: Heterodimer
Binding TFs: DLX3_TF2 (Homeobox domain)
TEAD4_TF1 (TEA/ATTS domain family)
DLX3_Crystal (Homeobox domain)
DLX3_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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