DNA Binding Motif

Accessions: TEAD4_FOXI1_2_3_4_5 (HumanTF2 1.0)
Names: TEAD4_FOXI1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 25
Consensus: rCaTtCCacmcysrmAgYGmmmaCA
Weblogo:
PSSM: P0 A C G T
01 29 0 17 0 r
02 9 46 0 0 C
03 46 0 15 12 a
04 2 3 0 46 T
05 7 12 0 39 t
06 0 46 1 11 C
07 0 46 3 11 C
08 26 4 9 7 a
09 3 23 10 11 c
10 20 18 8 0 m
11 9 22 4 11 c
12 4 18 5 18 y
13 4 14 18 11 s
14 13 0 26 8 r
15 12 22 6 5 m
16 32 5 4 5 A
17 4 8 24 10 g
18 1 32 0 13 Y
19 8 7 38 0 G
20 78 49 23 46 m
21 23 23 0 9 m
22 46 40 5 10 m
23 46 18 4 10 a
24 8 46 0 0 C
25 46 1 6 4 A
Type: Heterodimer
Binding TFs: FOXI1_TF2 (Fork head domain)
TEAD4_TF1 (TEA/ATTS domain family)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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