DNA Binding Motif

Accessions: TEAD4_RFX5_2 (HumanTF2 1.0)
Names: TEAD4_RFX5
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 29
Consensus: rCATwCCwwamksssyywwtwtrgyAACs
Weblogo:
PSSM: P0 A C G T
01 158 6 214 12 r
02 64 372 9 0 C
03 372 0 11 0 A
04 0 5 3 372 T
05 279 6 43 372 w
06 17 372 1 17 C
07 7 291 1 73 C
08 141 47 86 98 w
09 131 75 72 93 w
10 150 52 85 84 a
11 103 111 80 78 m
12 89 81 97 105 k
13 70 110 120 72 s
14 73 118 131 50 s
15 57 138 93 84 s
16 80 116 76 100 y
17 90 95 88 99 y
18 102 58 70 142 w
19 119 56 56 141 w
20 81 72 77 142 t
21 94 86 58 134 w
22 86 91 74 121 t
23 118 80 121 53 r
24 127 16 372 48 g
25 31 372 15 143 y
26 372 5 9 30 A
27 372 5 14 5 A
28 0 372 12 11 C
29 77 117 150 28 s
Type: Heterodimer
Binding TFs: RFX5_TF2 (RFX DNA-binding domain, Poxvirus D5 protein-like)
TEAD4_TF1 (TEA/ATTS domain family)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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