DNA Binding Motif

Accessions: 6ako_C (3D-footprint 20231221)
Names: Forkhead box protein C2
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of FOXC2 DBD Bound to DBE2 DNA
Length: 6
Consensus: TgtTTA
Weblogo:
PSSM: P0 A C G T
01 10 8 0 78 T
02 8 17 63 8 g
03 17 8 8 63 t
04 0 0 0 96 T
05 0 0 0 96 T
06 96 0 0 0 A
Binding TFs: 6ako_C (Fork head domain)
Binding Sites: 6ako_B
6ako_A
Publications: Chen X, Wei H, Li J, Liang X, Dai S, Jiang L, Guo M, Qu L, Chen Z, Chen L, Chen Y. Structural basis for DNA recognition by FOXC2. Nucleic Acids Res 47:3752-3764 (2019). [Pubmed]

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