DNA Binding Motif

						

			
Accessions: TEAD4_DLX3_2_3_4 (HumanTF2 1.0)

			
Names: TEAD4_DLX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: rCATwCCrmsyaATTA
Weblogo: 
PSSM: P0      A      C      G      T
01   1617     56   1461      5      r
02    386   3078     85      0      C
03   3078      0     11      9      A
04      0     10     22   3078      T
05   1960      0    206   3078      w
06     40   3078     45      6      C
07     23   3078      6    428      C
08   1026    398    979    674      r
09    770    932    705    671      m
10    686    995   1053    343      s
11    234   1840    215   1238      y
12   2031   1047    764    417      a
13   3078    485     96     62      A
14     92     33      8   3078      T
15     74    540     48   3078      T
16   3078     40    229     69      A
Type: Heterodimer
Binding TFs: DLX3_TF2 (Homeobox domain)
TEAD4_TF1 (TEA/ATTS domain family)
DLX3_Crystal (Homeobox domain)
DLX3_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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