DNA Binding Motif

						

			
Accessions: TEAD4_ETV7 (HumanTF2 1.0), UN0584.1 (JASPAR 2024)

			
Names: TEAD4_ETV7, TEAD4::ETV7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 20
Consensus: rGAATGCGGAAGyrytTCCg
Weblogo: 
PSSM: P0      A      C      G      T
01    174     26    263     17      r
02     46     75    417     18      G
03    410     48      2     81      A
04    449     14      3     23      A
05      1     35     11    433      T
06      7     13    438     14      G
07     19    438     10      2      C
08     21      2    448      0      G
09      0      2    447     16      G
10    425     31      0     39      A
11    415     24      5     58      A
12    113     26    333     16      G
13     74    140     26    263      y
14    203     73    124     49      r
15     10    237     10    195      y
16     54      6    108    282      t
17      0      0      4    450      T
18     19    444     14     34      C
19     19    431     11     26      C
20     57     77    217    100      g
Type: Heterodimer
Binding TFs: Q9Y603 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
TEAD4_TF1 (TEA/ATTS domain family)
ETV7_TF1 / ETV7_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
Q9Y603
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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