DNA Binding Motif

						

			
Accessions: MA0039.5 (JASPAR 2024)

			
Names: KLF4
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 8
Consensus: CCCCACCC
Weblogo: 
PSSM: P0      A      C      G      T
01   2465  49209   1583   2560      C
02   2105  47865   1214   4633      C
03   7021  45405   1422   1969      C
04   1173  52875    793    976      C
05  45602    161   6598   3456      A
06    852  52366   1470   1129      C
07   1617  51112   1870   1218      C
08   1202  51045   1005   2565      C
Type: Heterodimer
Binding TFs: O43474 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
O43474
Binding Sites: MA0039.5.17
MA0039.5.10
MA0039.5.18 / MA0039.5.2
MA0039.5.1 / MA0039.5.11 / MA0039.5.12 / MA0039.5.19 / MA0039.5.3 / MA0039.5.9
MA0039.5.4
MA0039.5.6 / MA0039.5.8
MA0039.5.13
MA0039.5.14 / MA0039.5.16
MA0039.5.15 / MA0039.5.5
MA0039.5.20
MA0039.5.7
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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