DNA Binding Motif

Accessions: 1f2i_IJ (3D-footprint 20231221)
Names: FUSION OF N-TERMINAL 17-MER PEPTIDE EXTENSION TO ZIF12
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: COCRYSTAL STRUCTURE OF SELECTED ZINC FINGER DIMER BOUND TO DNA
Length: 12
Consensus: TGGGCGCGCCCa
Weblogo:
PSSM: P0 A C G T
01 10 10 10 66 T
02 0 0 96 0 G
03 0 0 96 0 G
04 0 0 96 0 G
05 0 96 0 0 C
06 0 0 96 0 G
07 0 96 0 0 C
08 12 10 74 0 G
09 0 96 0 0 C
10 0 96 0 0 C
11 0 96 0 0 C
12 64 10 10 12 a
Binding TFs: 1f2i_I / 1f2i_J (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Sites: 1f2i_C / 1f2i_D
Publications: Wang B.S, Grant R.A, Pabo C.O. Selected peptide extension contacts hydrophobic patch on neighboring zinc finger and mediates dimerization on DNA. Nature structural biology 8:589-93 (2001). [Pubmed]

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