DNA Binding Motif

						

			
Accessions: TCF15 (HumanTF2 1.0), UN0580.1 (JASPAR 2024)

			
Names: TCF15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: HT-SELEX; HT-SELEX generated reference PWM, HT-SELEX
Length: 10
Consensus: aACAyRTGky
Weblogo: 
PSSM: P0      A      C      G      T
01   5466   3512   3210   2253      a
02  14442   3871   2248    612      A
03      0  14442      0      0      C
04  14442      0    137      0      A
05      0   7460    616   6982      y
06  14442   1196   5369      0      R
07      0    132      0  14442      T
08      0      0  14442      0      G
09    923   3304   5191   5024      k
10   2312   4417   1849   5864      y
Type: Heterodimer
Binding TFs: TCF15_TF2 (Helix-loop-helix DNA-binding domain)
Q12870 (Helix-loop-helix DNA-binding domain)
Q12870
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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