DNA Binding Motif

Accessions: 6oeo_ABN (3D-footprint 20231221)
Names: High mobility group protein B1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Cryo-EM structure of mouse RAG1/2 NFC complex (DNA1)
Length: 16
Consensus: GnnnnnnnnnnnTGTG
Weblogo:
PSSM: P0 A C G T
01 11 9 67 9 G
02 24 24 24 24 n
03 24 24 24 24 n
04 24 24 24 24 n
05 24 24 24 24 n
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 24 24 24 24 n
11 24 24 24 24 n
12 24 24 24 24 n
13 11 9 9 67 T
14 9 9 69 9 G
15 0 0 0 96 T
16 0 0 96 0 G
Binding TFs: 6oeo_N (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Binding Sites: 6oeo_F
6oeo_I
Publications: Chen X, Cui Y, Best RB, Wang H, Zhou ZH, Yang W, Gellert M. Cutting antiparallel DNA strands in a single active site. Nat Struct Mol Biol 27:119-126 (2020). [Pubmed]

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