DNA Binding Motif

Accessions: 4m9e_A (3D-footprint 20231221)
Names: Krueppel-like factor 4
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of Klf4 zinc finger DNA binding domain in complex with methylated DNA
Length: 10
Consensus: GAGGnnTGGC
Weblogo:
PSSM: P0 A C G T
01 9 9 69 9 G
02 96 0 0 0 A
03 0 0 96 0 G
04 0 0 96 0 G
05 24 24 24 24 n
06 24 24 24 24 n
07 0 0 0 96 T
08 0 0 96 0 G
09 9 9 69 9 G
10 9 69 9 9 C
Binding TFs: 4m9e_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Sites: 4m9e_B
4m9e_C
Publications: Liu Y, Olanrewaju Y.O, Zheng Y, Hashimoto H, Blumenthal R.M, Zhang X, Cheng X. Structural basis for Klf4 recognition of methylated DNA. Nucleic acids research 42:4859-67 (2014). [Pubmed]

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