DNA Binding Motif

						

			
Accessions: ETV2_PAX5 (HumanTF2 1.0)

			
Names: ETV2_PAX5
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: aCCGGAACyACGCwTsAcyg
Weblogo: 
PSSM: P0      A      C      G      T
01   3284    552    931    715      a
02    253   4048    429    113      C
03    414   3919     56      4      C
04      5      0   4290      0      G
05     48      0   4282     24      G
06   4279      0      0    192      A
07   3431     29     40    786      A
08    305   3158    227    596      C
09     81   1763     28   3511      y
10   4122   1218    220     90      A
11    311   3876    106    492      C
12    141    167   4232    107      G
13    174   4082   1038    327      C
14   1717    602     99   1868      w
15     45   1064    234   2943      T
16    145   2009   1744    388      s
17   2988    157    946    195      A
18    642   1948    849    847      c
19    207   1245    134   2990      y
20   1114    175   3152    295      g
Type: Heterodimer
Binding TFs: PAX5_TF1 / PAX5_TF2 ('Paired box' domain)
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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