DNA Binding Motif

Accessions: ATF4_TEF (HumanTF2 1.0)
Names: ATF4_TEF
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 13
Consensus: rkmTGAYGCAATm
Weblogo:
PSSM: P0 A C G T
01 936 85 2001 450 r
02 317 279 1568 772 k
03 1907 1029 263 0 m
04 9 0 23 2936 T
05 22 0 2936 13 G
06 2936 0 27 0 A
07 0 1244 2 2936 Y
08 0 22 2936 2 G
09 0 2936 0 81 C
10 2936 0 0 4 A
11 2936 0 8 0 A
12 52 513 52 2936 T
13 1463 1081 236 157 m
Type: Heterodimer
Binding TFs: ATF4_TF1 / ATF4_TF2 (bZIP transcription factor, Basic region leucine zipper)
TEF_TF1 / TEF_TF2 (bZIP transcription factor, Basic region leucine zipper)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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