DNA Binding Motif

Accessions: 3dzu_D (3D-footprint 20231221)
Names: Peroxisome proliferator-activated receptor gamma
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Intact PPAR gamma - RXR alpha Nuclear Receptor Complex on DNA bound with BVT.13, 9-cis Retinoic Acid and NCOA2 Peptide
Length: 11
Consensus: AAAnnAGGTcA
Weblogo:
PSSM: P0 A C G T
01 69 9 9 9 A
02 96 0 0 0 A
03 82 4 6 4 A
04 24 24 24 24 n
05 24 24 24 24 n
06 82 6 4 4 A
07 0 1 91 4 G
08 0 0 96 0 G
09 0 0 0 96 T
10 18 65 4 9 c
11 84 4 4 4 A
Binding TFs: 3dzu_D (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
Binding Sites: 3dzu_C
3dzu_F
Publications: Chandra V, Huang P, Hamuro Y, Raghuram S, Wang Y, Burris T.P, Rastinejad F. Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA. Nature 456:350-6 (2008). [Pubmed]

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