DNA Binding Motif

Accessions: 4y5w_BD (3D-footprint 20231221)
Names: Signal transducer and activator of transcription 6
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Transcription factor-DNA complex
Length: 7
Consensus: TTCnngg
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 0 0 0 96 T
03 0 96 0 0 C
04 24 24 24 24 n
05 24 24 24 24 n
06 13 16 54 13 g
07 16 13 54 13 g
Type: Heterodimer
Binding TFs: 4y5w_B (SH2 domain, STAT protein, all-alpha domain, STAT protein, DNA binding domain)
4y5w_D (SH2 domain, STAT protein, all-alpha domain, STAT protein, DNA binding domain)
Binding Sites: 4y5w_E
4y5w_F
Publications: Li J, Rodriguez JP, Niu F, Pu M, Wang J, Hung LW, Shao Q, Zhu Y, Ding W, Liu Y, Da Y, Yao Z, Yang J, Zhao Y, Wei GH, Cheng G, Liu ZJ, Ouyang S. Structural basis for DNA recognition by STAT6. Proc Natl Acad Sci U S A 113:13015-13020 (2016). [Pubmed]

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