DNA Binding Motif

						

			
Accessions: HOXB2_ETV7_1 (HumanTF2 1.0)

			
Names: HOXB2_ETV7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: TrATgrcsmGGAAryrCTTCCgs
Weblogo: 
PSSM: P0      A      C      G      T
01     17     36     13    345      T
02    345     21    145     66      r
03    345     16     35     15      A
04     15    113      0    345      T
05     35     13    248     96      g
06    169     12     99     64      r
07     54    136     81     74      c
08     15    136    132     61      s
09    111    192     29     13      m
10      2      3    345     25      G
11     16      6    323      0      G
12    314      7      4     19      A
13    254     29      8     54      A
14    131      2    211      0      r
15     38    100     32    174      y
16    197     37    111      0      r
17      0    345     44    100      C
18     14     16     26    345      T
19     32      6      6    345      T
20     18    345      0     28      C
21      4    345     11      3      C
22     14     54    218     59      g
23     75    153    108      9      s
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
ETV7_TF1 / ETV7_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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