DNA Binding Motif

						

			
Accessions: TEAD4_PITX1_2 (HumanTF2 1.0)

			
Names: TEAD4_PITX1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: rCATtccrtasGgATTA
Weblogo: 
PSSM: P0      A      C      G      T
01     64     31    133      4      r
02     25    197     28      2      C
03    197     18     15      4      A
04     11     17      0    197      T
05     56      0     45    141      t
06     37    197     25     31      c
07     23    125     14     35      c
08     66     46     53     32      r
09     42     42     45     68      t
10     87     43     46     21      a
11     26     58     72     40      s
12     28     40    197     18      G
13     10     42    197     48      g
14    197     20      5      0      A
15      1     12      1    197      T
16     28     31      8    197      T
17    197     15     30     17      A
Type: Heterodimer
Binding TFs: PITX1_TF1 / PITX1_TF2 (Homeobox domain)
TEAD4_TF1 (TEA/ATTS domain family)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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