DNA Binding Motif

						

			
Accessions: HOXB2_PITX1_2 (HumanTF2 1.0)

			
Names: HOXB2_PITX1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 13
Consensus: taATkrgGGATTA
Weblogo: 
PSSM: P0      A      C      G      T
01     52     18     46    245      t
02    245     30     77     28      a
03    245      0      0     23      A
04      0     27     54    245      T
05     31     34    118    127      k
06    140     11    105     10      r
07     45     50     95     55      g
08     13     10    245      6      G
09     15     58    245     17      G
10    245     43      2     23      A
11      0     16     11    245      T
12     27      9     23    245      T
13    245      0     13      0      A
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
PITX1_TF1 / PITX1_TF2 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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