DNA Binding Motif

Accessions: 3u3w_AB (3D-footprint 20231221)
Names: Transcriptional activator PlcR protein
Organisms: Bacillus thuringiensis
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of Bacillus thuringiensis PlcR in complex with the peptide PapR7 and DNA
Length: 16
Consensus: trTGAAnnnnTGCATa
Weblogo:
PSSM: P0 A C G T
01 16 8 8 64 t
02 56 8 24 8 r
03 0 0 0 96 T
04 0 0 96 0 G
05 96 0 0 0 A
06 96 0 0 0 A
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 24 24 24 24 n
11 0 0 0 96 T
12 0 0 96 0 G
13 0 96 0 0 C
14 96 0 0 0 A
15 0 0 0 96 T
16 64 16 8 8 a
Binding TFs: 3u3w_A / 3u3w_B (Helix-turn-helix, Helix-turn-helix domain)
Binding Sites: 3u3w_Y
3u3w_Z
Publications: Grenha R, Slamti L, Nicaise M, Refes Y, Lereclus D, Nessler S. Structural basis for the activation mechanism of the PlcR virulence regulator by the quorum-sensing signal peptide PapR. Proceedings of the National Academy of Sciences of the United States of America 110:1047-52 (2013). [Pubmed]

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