DNA Binding Motif

						

			
Accessions: TEAD4_MAX_2_3 (HumanTF2 1.0)

			
Names: TEAD4_MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: rmATwCCwcwhravCACGTG
Weblogo: 
PSSM: P0      A      C      G      T
01    801    131    609    124      r
02    610   1410    131     11      m
03   1410     35    173     11      A
04     50     26      0   1410      T
05    855     38    253   1410      w
06    175   1410    121    155      C
07    169   1410     55    334      C
08    501    249    295    365      w
09    311    470    279    351      c
10    473    300    257    381      w
11    371    437    240    362      h
12    374    286    401    349      r
13    604    277    316    213      a
14    369    553    378    110      v
15     33   1410      3      2      C
16   1410      0      0      0      A
17      0   1410      1    196      C
18     46      1   1410     12      G
19      9     47     10   1410      T
20     10      9   1410      8      G
Type: Heterodimer
Binding TFs: MAX_TF2 (Helix-loop-helix DNA-binding domain)
TEAD4_TF1 (TEA/ATTS domain family)
MAX_Full (Helix-loop-helix DNA-binding domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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