DNA Binding Motif

						

			
Accessions: 4xrm_AB (3D-footprint 20231221)

			
Names: Homeobox protein Meis2
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: homodimer of TALE type homeobox transcription factor MEIS1 complexes with specific DNA
Length: 12
Consensus: TGACAATTGTCA
Weblogo: 
PSSM: P0      A      C      G      T
01      5      6      5     80      T
02      0      0     96      0      G
03     96      0      0      0      A
04      0     96      0      0      C
05     80      5      5      6      A
06     80      6      5      5      A
07      6      5      5     80      T
08      5      6      5     80      T
09      0      0     96      0      G
10      0      0      0     96      T
11      0     96      0      0      C
12     80      5      6      5      A
Type: Heterodimer
Binding TFs: 4xrm_A (Homeobox domain, Homeobox KN domain)
4xrm_B (Homeobox domain, Homeobox KN domain)
Binding Sites: 4xrm_L
4xrm_M
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.