DNA Binding Motif

						

			
Accessions: POU5F1_methyl_1 (HT-SELEX2 May2017)

			
Names: POU5F1
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Length: 16
Consensus: rawTATGywAATkArg
Weblogo: 
PSSM: P0      A      C      G      T
01   3000   2460   3096   1798      r
02   7255   1560   3564   3099      a
03   3306    237    852   7048      w
04    129     17      1  10354      T
05  10354      1      0      3      A
06      5      0      1  10354      T
07      1      5  10354      0      G
08     14  10354    300   6222      y
09   7717      2     26  10354      w
10  10354      4      5      1      A
11  10354      0      0      1      A
12     27     50      0  10354      T
13     46    168   5342   5012      k
14  10354    528   1990   1495      A
15   5045   1836   5309    483      r
16    656   2356   5094   2249      g
Binding TFs: POU5F1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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