DNA Binding Motif

						

			
Accessions: 3kov_AB (3D-footprint 20231221)

			
Names: Myocyte-specific enhancer factor 2A
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of MEF2A bound to DNA reveals a completely folded MADS-box/MEF2 domain that recognizes DNA and recruits transcription co-factors
Length: 10
Consensus: TTAnnnnnAG
Weblogo: 
PSSM: P0      A      C      G      T
01     11      9      9     67      T
02      0      0      0     96      T
03     67      9     11      9      A
04     24     24     24     24      n
05     24     24     24     24      n
06     24     24     24     24      n
07     24     24     24     24      n
08     24     24     24     24      n
09     69      9      9      9      A
10      0      0     96      0      G
Binding TFs: 3kov_A / 3kov_B (SRF-type transcription factor (DNA-binding and dimerisation domain))
Binding Sites: 3kov_C
3kov_D
			
Publications: Wu Y, Dey R, Han A, Jayathilaka N, Philips M, Ye J, Chen L. Structure of the MADS-box/MEF2 domain of MEF2A bound to DNA and its implication for myocardin recruitment. Journal of molecular biology 397:520-33 (2010). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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