DNA Binding Motif

Accessions: UP00502B_1 (UniPROBE 20160601)
Names: S. purpuratus Tbrain (T-box transcription factor), SpTbr_rep2
Organisms: Strongylocentrotus purpuratus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 22
Consensus: smkvssgAGGTGyGAAmyrsdy
Weblogo:
PSSM: P0 A C G T
01 0.22 0.39 0.26 0.13 s
02 0.25 0.39 0.15 0.21 m
03 0.16 0.21 0.32 0.31 k
04 0.25 0.32 0.25 0.17 v
05 0.17 0.32 0.34 0.17 s
06 0.24 0.29 0.36 0.11 s
07 0.24 0.15 0.50 0.10 g
08 0.78 0 0.19 0.03 A
09 0.02 0.01 0.95 0.01 G
10 0 0.01 0.99 0 G
11 0 0.09 0 0.91 T
12 0 0 0.99 0 G
13 0.01 0.39 0 0.59 y
14 0 0.10 0.78 0.12 G
15 0.90 0 0.09 0 A
16 0.82 0.05 0.05 0.09 A
17 0.32 0.39 0.09 0.19 m
18 0.23 0.31 0.21 0.25 y
19 0.28 0.24 0.28 0.21 r
20 0.21 0.33 0.25 0.21 s
21 0.29 0.07 0.31 0.34 d
22 0.23 0.30 0.17 0.31 y
Binding TFs: UP00502B (T-box)
Binding Sites: AAGTGTGA
AGGTGCGA
AGGTGTCA
AGGTGTCG
AGGTGTGA
AGGTGTTA
AGTGTGAA
ATCACACC
GGGTGTGA
GGTGCGAA
GGTGTGAA
GTGTGAAA
GTGTGAAC
TCACACCA
AAGGTGTC
ACACCTCC
AGGTGTGG
AGGTGTTG
CACACCTC
CTCACACC
Publications: Cheatle Jarvela AM, Brubaker L, Vedenko A, Gupta A, Armitage BA, Bulyk ML, Hinman VF. Modular evolution of DNA-binding preference of a Tbrain transcription factor provides a mechanism for modifying gene regulatory networks. Mol Biol Evol 31:2672-88 (2014). [Pubmed]

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